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Absent in melanoma 2 inflammasome is required for host defence against Streptococcus pneumoniae infection
Streptococcus pneumoniae, a leading cause of invasive pneumococcal disease, is responsible for high mortality and morbidity worldwide. A previous study showed that the NLR family pyrin domain containing 3 (NLRP3) and absent in melanoma 2 (AIM2) inflammasomes are essential for caspase-1 activation an...
Autores principales: | Feng, Siwei, Chen, Tingting, Lei, Guihua, Hou, Fengqing, Jiang, Jiali, Huang, Qingyuan, Peng, Yuanyi, Ye, Chao, Hu, Dong-Liang, Fang, Rendong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900643/ https://www.ncbi.nlm.nih.gov/pubmed/31266383 http://dx.doi.org/10.1177/1753425919860252 |
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