Cargando…

MALAT1 modulates miR-146’s protection of microvascular endothelial cells against LPS-induced NF-κB activation and inflammatory injury

To investigate the role of miR-146 and its possible relationship with MALAT1 in LPS-induced inflammation in human microvascular endothelial cells (HMECs), HMEC-1 cells were treated with LPS to construct an inflammatory injury cell model, and the cell viability, TNF-α and IL-6 secretion and the expre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Feng, Lin-Lin, Xin, Wei-Na, Tian, Xiu-Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900645/ https://www.ncbi.nlm.nih.gov/pubmed/31291804 http://dx.doi.org/10.1177/1753425919861427

Ejemplares similares

miR-146a Attenuates Inflammatory Pathways Mediated by TLR4/NF-κB and TNFα to Protect Primary Human Retinal Microvascular Endothelial Cells Grown in High Glucose
por: Ye, Eun-Ah, et al.
Publicado: (2016)

miR-146b suppresses LPS-induced M1 macrophage polarization via inhibiting the FGL2-activated NF-κB/MAPK signaling pathway in inflammatory bowel disease
por: Pan, Yang, et al.
Publicado: (2022)

ROCK inhibitor fasudil reduces the expression of inflammatory factors in LPS-induced rat pulmonary microvascular endothelial cells via ROS/NF-κB pathway
por: Liu, Huanlong, et al.
Publicado: (2022)

Protective effect of MiR-146 on renal injury following cardiopulmonary bypass in rats through mediating NF-κB signaling pathway
por: Ma, Hongbo, et al.
Publicado: (2021)

Chikungunya Virus Exploits miR-146a to Regulate NF-κB Pathway in Human Synovial Fibroblasts
por: Selvamani, Sakthi Priya, et al.
Publicado: (2014)

Celastrol induces apoptosis of gastric cancer cells by miR-146a inhibition of NF-κB activity
por: Sha, Min, et al.
Publicado: (2013)

Toll-like 4 receptor /NFκB inflammatory/miR-146a pathway contributes to the ART-correlated preterm birth outcome
por: Zhong, Xinqi, et al.
Publicado: (2016)

Overexpression of miR-146a blocks the effect of LPS on RANKL-induced osteoclast differentiation
por: Gao, Yingjian, et al.
Publicado: (2018)

Therapeutic effect of Resveratrol in the treatment of osteoarthritis via the MALAT1/miR-9/NF-κB signaling pathway
por: Zhang, Guopeng, et al.
Publicado: (2020)

Acupuncture Decreases NF-κB p65, miR-155, and miR-21 and Increases miR-146a Expression in Chronic Atrophic Gastritis Rats
por: Zhang, Jialing, et al.
Publicado: (2016)

miRNA-146 negatively regulates the production of pro-inflammatory cytokines via NF-κB signalling in human gingival fibroblasts
por: Xie, Yu-feng, et al.
Publicado: (2014)

MALAT1 promotes liver fibrosis by sponging miR-181a and activating TLR4-NF-κB signaling
por: Wang, Yinghui, et al.
Publicado: (2021)

Paradoxical attenuation of neuroinflammatory response upon LPS challenge in miR-146b deficient mice
por: Chithanathan, Keerthana, et al.
Publicado: (2022)

Hyperglycemia-induced increasing of RELB/circ_0008590 in NF-κB pathway is repressed by miR-1243 in human retinal microvascular endothelial cells
por: Shao, Jun, et al.
Publicado: (2021)

Differential cell-intrinsic regulations of germinal center B and T cells by miR-146a and miR-146b
por: Cho, Sunglim, et al.
Publicado: (2018)

Increase in NF-κB-sensitive miRNA-146a and miRNA-155 in multiple sclerosis (MS) and pro-inflammatory neurodegeneration
por: Devier, Deidre J., et al.
Publicado: (2015)

Pinocembrin Protects Human Brain Microvascular Endothelial Cells against Fibrillar Amyloid-β (1−40)Injury by Suppressing the MAPK/NF-κB Inflammatory Pathways
por: Liu, Rui, et al.
Publicado: (2014)

miR-146a and miR-146b in the diagnosis and prognosis of papillary thyroid carcinoma
por: Qiu, Zhenwei, et al.
Publicado: (2017)

Ufm1 inhibits LPS-induced endothelial cell inflammatory responses through the NF-κB signaling pathway
por: Li, Yuan-Yuan, et al.
Publicado: (2017)

Andrographolide Protects against LPS-Induced Acute Lung Injury by Inactivation of NF-κB
por: Zhu, Tao, et al.
Publicado: (2013)

Dexmedetomidine Regulates the miR-146a-5p/NF-κB Axis to Alleviate Electroconvulsive Therapy-Induced Cognitive Impairments
por: Zhou, Xiaohui, et al.
Publicado: (2022)

NF-κB-Regulated miR-99a Modulates Endothelial Cell Inflammation
por: Bao, Mei-hua, et al.
Publicado: (2016)

Effects of acupuncture on the miR-146a-mediated IRAK1/TRAF6/NF-κB signaling pathway in rats with sarcopenia induced by D-galactose
por: Jin, Jing, et al.
Publicado: (2023)

The clinical value of lncRNA MALAT1 and its targets miR‐125b, miR‐133, miR‐146a, and miR‐203 for predicting disease progression in chronic obstructive pulmonary disease patients
por: Liu, Shuang, et al.
Publicado: (2020)

MIR222HG attenuates macrophage M2 polarization and allergic inflammation in allergic rhinitis by targeting the miR146a-5p/TRAF6/NF-κB axis
por: Wen, Silu, et al.
Publicado: (2023)

RAGE Plays a Role in LPS-Induced NF-κB Activation and Endothelial Hyperpermeability
por: Wang, Liqun, et al.
Publicado: (2017)

Protective effect of FOXP3-mediated miR-146b-5p/Robo1/NF-κB system on lipopolysaccharide-induced acute lung injury in mice
por: Zhu, Jiang, et al.
Publicado: (2020)

Downregulation of MALAT1 alleviates saturated fatty acid-induced myocardial inflammatory injury via the miR-26a/HMGB1/TLR4/NF-κB axis
por: Jia, Pengyu, et al.
Publicado: (2019)

miR-146a-mediated suppression of the inflammatory response in human adipocytes
por: Roos, Julian, et al.
Publicado: (2016)

Involvement of inflammation-related miR-155 and miR-146a in diabetic nephropathy: implications for glomerular endothelial injury
por: Huang, Youqun, et al.
Publicado: (2014)

HSV-1\EGFP stimulates miR-146a expression in a NF-κB-dependent manner in monocytic THP-1 cells
por: Venuti, Assunta, et al.
Publicado: (2019)

Epstein-Barr virus BARF1-induced NFκB/miR-146a/SMAD4 alterations in stomach cancer cells
por: Kim, Dong Ha, et al.
Publicado: (2016)

FOXP3-microRNA-146-NF-κB as oncotarget
por: Etikala, Deepa M., et al.
Publicado: (2015)

Suppression of lncRNA MALAT1 Reduces LPS- or IL-17A-Induced Inflammatory Response in Human Middle Ear Epithelial Cells via the NF-κB Signaling Pathway
por: Yang, Xiangru, et al.
Publicado: (2021)

Down-regulation of miR-146b-5p by long noncoding RNA MALAT1 in hepatocellular carcinoma promotes cancer growth and metastasis
por: Li, Chao, et al.
Publicado: (2017)

MiR-146a in Immunity and Disease
por: Rusca, Nicole, et al.
Publicado: (2011)

Anti-inflammatory effects of guggulsterone on murine macrophage by inhibiting LPS-induced inflammatory cytokines in NF-κB signaling pathway
por: Zhang, Jin-Hua, et al.
Publicado: (2016)

Nicorandil Attenuates LPS-Induced Acute Lung Injury by Pulmonary Endothelial Cell Protection via NF-κB and MAPK Pathways
por: He, Mengyu, et al.
Publicado: (2019)

miR-146a, miR-221, and miR-155 are Involved in Inflammatory Immune Response in Severe COVID-19 Patients
por: Gaytán-Pacheco, Noemí, et al.
Publicado: (2022)

Helminth Excreted/Secreted Antigens Repress Expression of LPS-Induced Let-7i but Not miR-146a and miR-155 in Human Dendritic Cells
por: Terrazas, Luis I., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_dim6l556ppbig5tsuevp9mvdmt