Gender differences of cannabis smoking on serum leptin levels: population-based study

OBJECTIVE: To evaluate the serum leptin levels in cannabis smokers. METHODS: This was a cross-sectional population-based study of participants between the ages of 18 and 35 years. The data were collected through a self-administered questionnaire covering sociodemographic data and the use of psychoac...

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Detalles Bibliográficos
Autores principales: Moreira, Fernanda P., Wiener, Carolina D., de Oliveira, Jacqueline F., Souza, Luciano D.M., da Silva, Ricardo A., Portela, Luis V., Lara, Diogo R., Jansen, Karen, Oses, Jean Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Psiquiatria 2018
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900773/
https://www.ncbi.nlm.nih.gov/pubmed/29412334
http://dx.doi.org/10.1590/1516-4446-2017-2231
Descripción
Sumario:OBJECTIVE: To evaluate the serum leptin levels in cannabis smokers. METHODS: This was a cross-sectional population-based study of participants between the ages of 18 and 35 years. The data were collected through a self-administered questionnaire covering sociodemographic data and the use of psychoactive substances. Leptin levels were measured using a commercial ELISA kit. RESULTS: Of the 911 participants, 6.7% were identified as cannabis smokers and had significantly lower leptin levels (p = 0.008). When stratified by gender, there was a significant decrease in leptin levels among male smokers (p = 0.039). CONCLUSION: Cannabis smoking was linked to leptin levels in men, suggesting that the response to biological signals may be different between men and women.

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