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Reconstituting Drosophila Centromere Identity in Human Cells

The centromere is an essential chromosomal region required for accurate chromosome segregation. Most eukaryotic centromeres are defined epigenetically by the histone H3 variant, centromere protein (CENP)-A, yet how its self-propagation is achieved remains poorly understood. Here, we develop a hetero...

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Detalles Bibliográficos
Autores principales:	Roure, Virginie, Medina-Pritchard, Bethan, Lazou, Vasiliki, Rago, Luciano, Anselm, Eduard, Venegas, Daniela, Jeyaprakash, A. Arockia, Heun, Patrick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900781/ https://www.ncbi.nlm.nih.gov/pubmed/31597104 http://dx.doi.org/10.1016/j.celrep.2019.08.067

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