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IKKβ Inhibitor IMD-0354 Attenuates Radiation Damage in Whole-body X-Irradiated Mice

Nuclear factor-kappa B (NF-κB) transcription factor plays a critical role in regulating radiation-induced inflammatory and immune responses. Intracellular reactive oxygen species generation induces the activation of NF-κB via the inhibitor of κB (IκB) kinase (IKK) complex signaling. Previous studies...

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Detalles Bibliográficos
Autores principales:	Waga, Kengo, Yamaguchi, Masaru, Miura, Shuta, Nishida, Teruki, Itai, Akiko, Nakanishi, Reiko, Kashiwakura, Ikuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900939/ https://www.ncbi.nlm.nih.gov/pubmed/31885799 http://dx.doi.org/10.1155/2019/5340290

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