Cargando…

BTBD7 Downregulates E-Cadherin and Promotes Epithelial-Mesenchymal Transition in Lung Cancer

Metastasis is the leading cause of lung cancer-associated death. Downregulated expression of E-cadherin followed by epithelial-mesenchymal transition (EMT) is critical for metastasis initiation in lung cancer. BTBD7 plays essential roles in lung cancer metastasis, but the mechanisms remain unknown....

Descripción completa

Detalles Bibliográficos
Autores principales:	Shu, Jie, Wang, Lin, Han, Fei, Chen, Yubin, Wang, Shunjun, Luo, Fanyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900955/ https://www.ncbi.nlm.nih.gov/pubmed/31886230 http://dx.doi.org/10.1155/2019/5937635

Ejemplares similares

Silencing of Btbd7 Inhibited Epithelial–Mesenchymal Transition and Chemoresistance in CD133(+) Lung Carcinoma A549 Cells
por: Fang, Li-Zhou, et al.
Publicado: (2017)

Btbd7 contributes to reduced E-cadherin expression and predicts poor prognosis in non-small cell lung cancer
por: Fan, Chuifeng, et al.
Publicado: (2014)

Artesunate inhibits epithelial-mesenchymal transition in non-small-cell lung cancer (NSCLC) cells by down-regulating the expression of BTBD7
por: Wang, Jing-Si, et al.
Publicado: (2020)

E-cadherin on epithelial–mesenchymal transition in thyroid cancer
por: Zhu, Xiaoyu, et al.
Publicado: (2021)

E-cadherin transcriptional downregulation by promoter methylation but not mutation is related to epithelial-to-mesenchymal transition in breast cancer cell lines
por: Lombaerts, M, et al.
Publicado: (2006)

The Role of BTBD7 in Normal Development and Tumor Progression
por: Liu, Yun, et al.
Publicado: (2023)

Chlamydia trachomatis Infection Is Associated with E-Cadherin Promoter Methylation, Downregulation of E-Cadherin Expression, and Increased Expression of Fibronectin and α-SMA—Implications for Epithelial-Mesenchymal Transition
por: Rajić, Jovana, et al.
Publicado: (2017)

Antitumor activity of RUNX3: Upregulation of E-cadherin and downregulation of the epithelial–mesenchymal transition in clear-cell renal cell carcinoma
por: Yang, Ruo-Nan, et al.
Publicado: (2022)

The E-Cadherin and N-Cadherin Switch in Epithelial-to-Mesenchymal Transition: Signaling, Therapeutic Implications, and Challenges
por: Loh, Chin-Yap, et al.
Publicado: (2019)

VEGF Mediates Tumor Growth and Metastasis by Affecting the Expression of E-Cadherin and N-Cadherin Promoting Epithelial to Mesenchymal Transition in Gastric Cancer
por: Zhang, Yue, et al.
Publicado: (2023)

SIRT1 induces epithelial-mesenchymal transition by promoting autophagic degradation of E-cadherin in melanoma cells
por: Sun, Ting, et al.
Publicado: (2018)

BTBD10 inhibits glioma tumorigenesis by downregulating cyclin D1 and p-Akt
por: Liu, Yu, et al.
Publicado: (2022)

Metformin Inhibits the Expression of Biomarkers of Fibrosis of EPCs In Vitro
por: Han, Fei, et al.
Publicado: (2019)

Role of epithelial-mesenchymal transition markers E-cadherin, N-cadherin, β-catenin and ZEB2 in laryngeal squamous cell carcinoma
por: Zhu, Guang-Jie, et al.
Publicado: (2018)

Loss of E-cadherin and epithelial to mesenchymal transition is not required for cell motility in tissues or for metastasis
por: Liu, Xiang, et al.
Publicado: (2014)

Roles of E-cadherin and Noncoding RNAs in the Epithelial–mesenchymal Transition and Progression in Gastric Cancer
por: Bure, Irina V., et al.
Publicado: (2019)

Significance of E-cadherin and Vimentin as epithelial-mesenchymal transition markers in colorectal carcinoma prognosis
por: Niknami, Zohreh, et al.
Publicado: (2020)

TGF-β1-induced epithelial–mesenchymal transition in lung cancer cells involves upregulation of miR-9 and downregulation of its target, E-cadherin
por: Wang, Hui, et al.
Publicado: (2017)

Disabled-2 downregulation promotes epithelial-to-mesenchymal transition
por: Martin, J C, et al.
Publicado: (2010)

Breast carcinoma cells re-express E-cadherin during mesenchymal to epithelial reverting transition
por: Chao, Yvonne L, et al.
Publicado: (2010)

Identification of circular RNA BTBD7_hsa_circ_0000563 as a novel biomarker for coronary artery disease and the functional discovery of BTBD7_hsa_circ_0000563 based on peripheral blood mononuclear cells: a case control study
por: Zhou, Hanxiao, et al.
Publicado: (2022)

Characterization of BTBD1 and BTBD2, two similar BTB-domain-containing Kelch-like proteins that interact with Topoisomerase I
por: Xu, Lixin, et al.
Publicado: (2002)

Association of BTBD7 with Metastasis and Poor Prognosis in Non-Small-Cell Lung Cancer Patients
por: Luo, Fan-Yan, et al.
Publicado: (2015)

High BTBD7 expression positive is correlated with SLUG-predicted poor prognosis in hormone receptor-negative breast cancer
por: Li, Zi-Xiong, et al.
Publicado: (2021)

Downregulation of iNOS/NO Promotes Epithelial–Mesenchymal Transition and Metastasis in Colorectal Cancer
por: Du, Qiang, et al.
Publicado: (2023)

MiR-429 reverses epithelial-mesenchymal transition by restoring E-cadherin expression in bladder cancer
por: Wu, Chia-Lun, et al.
Publicado: (2016)

Oncogenic effect of PHLDB2 is associated with epithelial–mesenchymal transition and E-cadherin regulation in colorectal cancer
por: Chen, Geng, et al.
Publicado: (2019)

Distinct Mesenchymal Alterations in N-Cadherin and E-Cadherin Positive Primary Renal Epithelial Cells
por: Keller, Christof, et al.
Publicado: (2012)

Downregulation of TRIM33 Promotes Survival and Epithelial–Mesenchymal Transition in Gastric Cancer
por: Wang, Fang, et al.
Publicado: (2022)

The Role of BTBD9 in Striatum and Restless Legs Syndrome
por: Lyu, Shangru, et al.
Publicado: (2019)

Downregulation of 26S proteasome catalytic activity promotes epithelial-mesenchymal transition
por: Banno, Asoka, et al.
Publicado: (2016)

An hTERT/ZEB1 complex directly regulates E-cadherin to promote epithelial-to-mesenchymal transition (EMT) in colorectal cancer
por: Qin, Yong, et al.
Publicado: (2015)

Long Noncoding RNA TCONS_00068220 Promotes Breast Cancer Progression by Regulating Epithelial-Mesenchymal Transition Marker E-Cadherin
por: Liu, Xiao, et al.
Publicado: (2021)

Loss of E-cadherin expression is not a prerequisite for c-erbB2-induced epithelial-mesenchymal transition
por: NILSSON, GISELA M.A., et al.
Publicado: (2014)

Loss of E-cadherin and Acquisition of Vimentin in Epithelial-Mesenchymal Transition are Noble Indicators of Uterine Cervix Cancer Progression
por: Myong, Na-Hye
Publicado: (2012)

Small molecule/ML327 mediated transcriptional de-repression of E-cadherin and inhibition of epithelial-to-mesenchymal transition
por: An, Hanbing, et al.
Publicado: (2015)

PHF8 upregulation contributes to autophagic degradation of E-cadherin, epithelial-mesenchymal transition and metastasis in hepatocellular carcinoma
por: Zhou, Wuhua, et al.
Publicado: (2018)

Role of N-Cadherin in Epithelial-to-Mesenchymal Transition and Chemosensitivity of Colon Carcinoma Cells
por: Skarkova, Veronika, et al.
Publicado: (2022)

HIF-2α promotes epithelial-mesenchymal transition through regulating Twist2 binding to the promoter of E-cadherin in pancreatic cancer
por: Yang, Jian, et al.
Publicado: (2016)

Histone acetyltransferase CSRP2BP promotes the epithelial–mesenchymal transition and metastasis of cervical cancer cells by activating N-cadherin
por: Yang, Xiaohui, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_2574l5udef8812p0ibsb9qt947