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Frailty Screening in Chronic Kidney Disease: Current Perspectives
Frailty has been defined as a state of increased vulnerability as a consequence of deficit accumulation. Frailty screening has not yet been widely implemented into routine nephrology care. Patients with chronic kidney disease (CKD) are at high risk of being frail, and frailty has been associated wit...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901033/ https://www.ncbi.nlm.nih.gov/pubmed/31824188 http://dx.doi.org/10.2147/IJNRD.S228956 |
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author | Worthen, George Tennankore, Karthik |
author_facet | Worthen, George Tennankore, Karthik |
author_sort | Worthen, George |
collection | PubMed |
description | Frailty has been defined as a state of increased vulnerability as a consequence of deficit accumulation. Frailty screening has not yet been widely implemented into routine nephrology care. Patients with chronic kidney disease (CKD) are at high risk of being frail, and frailty has been associated with worse outcomes in this population. Standard management of CKD, including initiation of renal replacement therapies, may have decreased benefit or potentially cause harm in the presence of frailty, and a variety of interventions for modifying frailty in the CKD population have been proposed. The optimal means of screening for frailty in patients with kidney disease remains unclear. This review highlights the value of frailty screening in CKD by summarizing the outcomes associated with frailty and exploring proposed changes to the management of frail patients with CKD. Finally, we will propose a framework for how to implement frailty screening into standard nephrology care. |
format | Online Article Text |
id | pubmed-6901033 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-69010332019-12-10 Frailty Screening in Chronic Kidney Disease: Current Perspectives Worthen, George Tennankore, Karthik Int J Nephrol Renovasc Dis Review Frailty has been defined as a state of increased vulnerability as a consequence of deficit accumulation. Frailty screening has not yet been widely implemented into routine nephrology care. Patients with chronic kidney disease (CKD) are at high risk of being frail, and frailty has been associated with worse outcomes in this population. Standard management of CKD, including initiation of renal replacement therapies, may have decreased benefit or potentially cause harm in the presence of frailty, and a variety of interventions for modifying frailty in the CKD population have been proposed. The optimal means of screening for frailty in patients with kidney disease remains unclear. This review highlights the value of frailty screening in CKD by summarizing the outcomes associated with frailty and exploring proposed changes to the management of frail patients with CKD. Finally, we will propose a framework for how to implement frailty screening into standard nephrology care. Dove 2019-12-05 /pmc/articles/PMC6901033/ /pubmed/31824188 http://dx.doi.org/10.2147/IJNRD.S228956 Text en © 2019 Worthen and Tennankore. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Review Worthen, George Tennankore, Karthik Frailty Screening in Chronic Kidney Disease: Current Perspectives |
title | Frailty Screening in Chronic Kidney Disease: Current Perspectives |
title_full | Frailty Screening in Chronic Kidney Disease: Current Perspectives |
title_fullStr | Frailty Screening in Chronic Kidney Disease: Current Perspectives |
title_full_unstemmed | Frailty Screening in Chronic Kidney Disease: Current Perspectives |
title_short | Frailty Screening in Chronic Kidney Disease: Current Perspectives |
title_sort | frailty screening in chronic kidney disease: current perspectives |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901033/ https://www.ncbi.nlm.nih.gov/pubmed/31824188 http://dx.doi.org/10.2147/IJNRD.S228956 |
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