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In vivo Studies on Pharmacokinetics, Toxicity and Immunogenicity of Polyelectrolyte Nanocapsules Functionalized with Two Different Polymers: Poly-L-Glutamic Acid or PEG

BACKGROUND: The functionalization of a nanoparticle surface with PEG (polyethylene glycol) is an approach most often used for extending nanomaterial circulation time, enhancing its delivery and retention in the target tissues, and decreasing systemic toxicity of nanocarriers and their cargos. Howeve...

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Detalles Bibliográficos
Autores principales: Karabasz, Alicja, Szczepanowicz, Krzysztof, Cierniak, Agnieszka, Mezyk-Kopec, Renata, Dyduch, Grzegorz, Szczęch, Marta, Bereta, Joanna, Bzowska, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901045/
https://www.ncbi.nlm.nih.gov/pubmed/31824153
http://dx.doi.org/10.2147/IJN.S230865

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