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Recurrent somatic mutations reveal new insights into consequences of mutagenic processes in cancer
The sheer size of the human genome makes it improbable that identical somatic mutations at the exact same position are observed in multiple tumours solely by chance. The scarcity of cancer driver mutations also precludes positive selection as the sole explanation. Therefore, recurrent mutations may...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901237/ https://www.ncbi.nlm.nih.gov/pubmed/31765368 http://dx.doi.org/10.1371/journal.pcbi.1007496 |