Evolutionarily conserved long-chain Acyl-CoA synthetases regulate membrane composition and fluidity

The human AdipoR1 and AdipoR2 proteins, as well as their C. elegans homolog PAQR-2, protect against cell membrane rigidification by exogenous saturated fatty acids by regulating phospholipid composition. Here, we show that mutations in the C. elegans gene acs-13 help to suppress the phenotypes of pa...

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Detalles Bibliográficos
Autores principales: Ruiz, Mario, Bodhicharla, Rakesh, Ståhlman, Marcus, Svensk, Emma, Busayavalasa, Kiran, Palmgren, Henrik, Ruhanen, Hanna, Boren, Jan, Pilon, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901333/
https://www.ncbi.nlm.nih.gov/pubmed/31769755
http://dx.doi.org/10.7554/eLife.47733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901333/
https://www.ncbi.nlm.nih.gov/pubmed/31769755
http://dx.doi.org/10.7554/eLife.47733

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