Idiosyncratic Reaction Causing a Rare Side Effect: Isotretenoin-induced Pancreatitis

Isotretinoin is a frequently prescribed medication for severe nodulocystic acne. It is also used in higher doses and other forms to treat some carcinomas. Pancreatitis remains a well-known but rare side effect of this medication. Two proposed mechanisms for pancreatitis are hypertriglyceridemia indu...

Descripción completa

Detalles Bibliográficos
Autores principales: Atiq, Muhammad Umair, Raza, Ahmad, Ashfaq, Ammar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Gastroenterology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901366/
https://www.ncbi.nlm.nih.gov/pubmed/31886043
http://dx.doi.org/10.7759/cureus.6102
_version_ 1783477483242258432
author Atiq, Muhammad Umair
Raza, Ahmad
Ashfaq, Ammar
author_facet Atiq, Muhammad Umair
Raza, Ahmad
Ashfaq, Ammar
author_sort Atiq, Muhammad Umair
collection PubMed
description Isotretinoin is a frequently prescribed medication for severe nodulocystic acne. It is also used in higher doses and other forms to treat some carcinomas. Pancreatitis remains a well-known but rare side effect of this medication. Two proposed mechanisms for pancreatitis are hypertriglyceridemia induced and idiosyncratic reaction. Here, we present a case of a young man who presented for the evaluation of abdominal pain. His blood work showed elevated lipase levels but computed tomography (CT) of the abdomen did not show any pancreatic inflammation.
format Online
Article
Text
id pubmed-6901366
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-69013662019-12-29 Idiosyncratic Reaction Causing a Rare Side Effect: Isotretenoin-induced Pancreatitis Atiq, Muhammad Umair Raza, Ahmad Ashfaq, Ammar Cureus Gastroenterology Isotretinoin is a frequently prescribed medication for severe nodulocystic acne. It is also used in higher doses and other forms to treat some carcinomas. Pancreatitis remains a well-known but rare side effect of this medication. Two proposed mechanisms for pancreatitis are hypertriglyceridemia induced and idiosyncratic reaction. Here, we present a case of a young man who presented for the evaluation of abdominal pain. His blood work showed elevated lipase levels but computed tomography (CT) of the abdomen did not show any pancreatic inflammation. Cureus 2019-11-08 /pmc/articles/PMC6901366/ /pubmed/31886043 http://dx.doi.org/10.7759/cureus.6102 Text en Copyright © 2019, Atiq et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Gastroenterology
Atiq, Muhammad Umair
Raza, Ahmad
Ashfaq, Ammar
Idiosyncratic Reaction Causing a Rare Side Effect: Isotretenoin-induced Pancreatitis
title Idiosyncratic Reaction Causing a Rare Side Effect: Isotretenoin-induced Pancreatitis
title_full Idiosyncratic Reaction Causing a Rare Side Effect: Isotretenoin-induced Pancreatitis
title_fullStr Idiosyncratic Reaction Causing a Rare Side Effect: Isotretenoin-induced Pancreatitis
title_full_unstemmed Idiosyncratic Reaction Causing a Rare Side Effect: Isotretenoin-induced Pancreatitis
title_short Idiosyncratic Reaction Causing a Rare Side Effect: Isotretenoin-induced Pancreatitis
title_sort idiosyncratic reaction causing a rare side effect: isotretenoin-induced pancreatitis
topic Gastroenterology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901366/
https://www.ncbi.nlm.nih.gov/pubmed/31886043
http://dx.doi.org/10.7759/cureus.6102
work_keys_str_mv AT atiqmuhammadumair idiosyncraticreactioncausingararesideeffectisotretenoininducedpancreatitis
AT razaahmad idiosyncraticreactioncausingararesideeffectisotretenoininducedpancreatitis
AT ashfaqammar idiosyncraticreactioncausingararesideeffectisotretenoininducedpancreatitis

Ejemplares similares