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Hepatic Sarcoidosis: An Uncommon Cause of Cirrhosis

Sarcoidosis is a multi-organ inflammatory disease of unclear etiology. The hallmark of the disease is the formation of non-caseating granulomas. The prevalence of sarcoidosis is 5-30% in the general population and up to 80% in autopsy series. Hepatic involvement is seen in almost 50% of cases of sar...

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Detalles Bibliográficos
Autores principales: Ghoneim, Sara, Williams, Sherrie D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901370/
https://www.ncbi.nlm.nih.gov/pubmed/31857928
http://dx.doi.org/10.7759/cureus.6316
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author Ghoneim, Sara
Williams, Sherrie D
author_facet Ghoneim, Sara
Williams, Sherrie D
author_sort Ghoneim, Sara
collection PubMed
description Sarcoidosis is a multi-organ inflammatory disease of unclear etiology. The hallmark of the disease is the formation of non-caseating granulomas. The prevalence of sarcoidosis is 5-30% in the general population and up to 80% in autopsy series. Hepatic involvement is seen in almost 50% of cases of sarcoidosis, though the clinical consequences are variable. In this study, we describe the case of three patients from our institution with hepatic sarcoidosis. Two of them eventually went on to develop liver cirrhosis.
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spelling pubmed-69013702019-12-19 Hepatic Sarcoidosis: An Uncommon Cause of Cirrhosis Ghoneim, Sara Williams, Sherrie D Cureus Gastroenterology Sarcoidosis is a multi-organ inflammatory disease of unclear etiology. The hallmark of the disease is the formation of non-caseating granulomas. The prevalence of sarcoidosis is 5-30% in the general population and up to 80% in autopsy series. Hepatic involvement is seen in almost 50% of cases of sarcoidosis, though the clinical consequences are variable. In this study, we describe the case of three patients from our institution with hepatic sarcoidosis. Two of them eventually went on to develop liver cirrhosis. Cureus 2019-12-06 /pmc/articles/PMC6901370/ /pubmed/31857928 http://dx.doi.org/10.7759/cureus.6316 Text en Copyright © 2019, Ghoneim et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Gastroenterology
Ghoneim, Sara
Williams, Sherrie D
Hepatic Sarcoidosis: An Uncommon Cause of Cirrhosis
title Hepatic Sarcoidosis: An Uncommon Cause of Cirrhosis
title_full Hepatic Sarcoidosis: An Uncommon Cause of Cirrhosis
title_fullStr Hepatic Sarcoidosis: An Uncommon Cause of Cirrhosis
title_full_unstemmed Hepatic Sarcoidosis: An Uncommon Cause of Cirrhosis
title_short Hepatic Sarcoidosis: An Uncommon Cause of Cirrhosis
title_sort hepatic sarcoidosis: an uncommon cause of cirrhosis
topic Gastroenterology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901370/
https://www.ncbi.nlm.nih.gov/pubmed/31857928
http://dx.doi.org/10.7759/cureus.6316
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