Interaction between androgen receptor and coregulator SLIRP is regulated by Ack1 tyrosine kinase and androgen

Aberrant activation of the androgen receptor (AR) may play a critical role in castration resistant prostate cancer. After ligand binding, AR is recruited to the androgen responsive element (ARE) sequences on the DNA where AR interaction with coactivators and corepressors modulates transcription. We...

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Detalles Bibliográficos
Autores principales: De Silva, Dinuka, Zhang, Zhentao, Liu, Yuanbo, Parker, Joel S., Xu, Chenxi, Cai, Ling, Wang, Gang Greg, Earp, H. Shelton, Whang, Young E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901447/
https://www.ncbi.nlm.nih.gov/pubmed/31819114
http://dx.doi.org/10.1038/s41598-019-55057-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901447/
https://www.ncbi.nlm.nih.gov/pubmed/31819114
http://dx.doi.org/10.1038/s41598-019-55057-2

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