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A Novel Polysaccharide Depolymerase Encoded by the Phage SH-KP152226 Confers Specific Activity Against Multidrug-Resistant Klebsiella pneumoniae via Biofilm Degradation

The increasing prevalence of infections caused by multidrug-resistant Klebsiella pneumoniae necessitates the development of alternative therapies. Here, we isolated, characterized, and sequenced a K. pneumoniae bacteriophage (SH-KP152226) that specifically infects and lyses K. pneumoniae capsular ty...

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Detalles Bibliográficos
Autores principales: Wu, Yunqiang, Wang, Rui, Xu, Mengsha, Liu, Yanan, Zhu, Xianchao, Qiu, Jiangfeng, Liu, Qiming, He, Ping, Li, Qingtian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901502/
https://www.ncbi.nlm.nih.gov/pubmed/31849905
http://dx.doi.org/10.3389/fmicb.2019.02768