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Sodium Channel Na(v)1.5 Controls Epithelial-to-Mesenchymal Transition and Invasiveness in Breast Cancer Cells Through its Regulation by the Salt-Inducible Kinase-1

Loss of epithelial polarity and gain in invasiveness by carcinoma cells are critical events in the aggressive progression of cancers and depend on phenotypic transition programs such as the epithelial-to-mesenchymal transition (EMT). Many studies have reported the aberrant expression of voltage-gate...

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Detalles Bibliográficos
Autores principales: Gradek, Frédéric, Lopez-Charcas, Osbaldo, Chadet, Stéphanie, Poisson, Lucile, Ouldamer, Lobna, Goupille, Caroline, Jourdan, Marie-Lise, Chevalier, Stéphan, Moussata, Driffa, Besson, Pierre, Roger, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901527/
https://www.ncbi.nlm.nih.gov/pubmed/31819138
http://dx.doi.org/10.1038/s41598-019-55197-5