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Clinically Approved Drugs Inhibit the Staphylococcus aureus Multidrug NorA Efflux Pump and Reduce Biofilm Formation
Staphylococcus aureus has acquired resistance to antibiotics since their first use. The S. aureus protein NorA, an efflux pump belonging to the major facilitator superfamily (MFS), contributes to resistance to fluoroquinolones (e.g., ciprofloxacin), biocides, dyes, quaternary ammonium compounds, and...
Autores principales: | Zimmermann, Saskia, Klinger-Strobel, Mareike, Bohnert, Jürgen A., Wendler, Sindy, Rödel, Jürgen, Pletz, Mathias W., Löffler, Bettina, Tuchscherr, Lorena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901667/ https://www.ncbi.nlm.nih.gov/pubmed/31849901 http://dx.doi.org/10.3389/fmicb.2019.02762 |
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