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Diagnostic Profiling of the Human Public IgM Repertoire With Scalable Mimotope Libraries
Specific antibody reactivities are routinely used as biomarkers, but the antibody repertoire reactivity (igome) profiles are still neglected. Here, we propose rationally designed peptide arrays as efficient probes for these system level biomarkers. Most IgM antibodies are characterized by few somati...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901697/ https://www.ncbi.nlm.nih.gov/pubmed/31849974 http://dx.doi.org/10.3389/fimmu.2019.02796 |