Anti-Hu Antibody-Associated Adie's Pupil and Paraneoplastic Sensorimotor Polyneuropathy Caused by Primary Mediastinal Small Cell Carcinoma

We report a woman with unilateral Adie's pupil associated with peripheral sensorimotor polyneuropathy, elevated anti-Hu antibody, and primary mediastinal small cell carcinoma (SCC). To our knowledge, this is the first report of Adie's pupil in a patient with mediastinal SCC. Although rare,...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Lei, Luo, Si, Jin, Hui, Lv, Xueman, Chen, Jiajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901962/
https://www.ncbi.nlm.nih.gov/pubmed/31849812
http://dx.doi.org/10.3389/fneur.2019.01236
_version_ 1783477593430818816
author Zhang, Lei
Luo, Si
Jin, Hui
Lv, Xueman
Chen, Jiajun
author_facet Zhang, Lei
Luo, Si
Jin, Hui
Lv, Xueman
Chen, Jiajun
author_sort Zhang, Lei
collection PubMed
description We report a woman with unilateral Adie's pupil associated with peripheral sensorimotor polyneuropathy, elevated anti-Hu antibody, and primary mediastinal small cell carcinoma (SCC). To our knowledge, this is the first report of Adie's pupil in a patient with mediastinal SCC. Although rare, Adie's pupil and sensorimotor polyneuropathy may be the first manifestation of cancer. Its rapid recognition facilitates an early diagnosis and treatment.
format Online
Article
Text
id pubmed-6901962
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-69019622019-12-17 Anti-Hu Antibody-Associated Adie's Pupil and Paraneoplastic Sensorimotor Polyneuropathy Caused by Primary Mediastinal Small Cell Carcinoma Zhang, Lei Luo, Si Jin, Hui Lv, Xueman Chen, Jiajun Front Neurol Neurology We report a woman with unilateral Adie's pupil associated with peripheral sensorimotor polyneuropathy, elevated anti-Hu antibody, and primary mediastinal small cell carcinoma (SCC). To our knowledge, this is the first report of Adie's pupil in a patient with mediastinal SCC. Although rare, Adie's pupil and sensorimotor polyneuropathy may be the first manifestation of cancer. Its rapid recognition facilitates an early diagnosis and treatment. Frontiers Media S.A. 2019-11-26 /pmc/articles/PMC6901962/ /pubmed/31849812 http://dx.doi.org/10.3389/fneur.2019.01236 Text en Copyright © 2019 Zhang, Luo, Jin, Lv and Chen. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Zhang, Lei
Luo, Si
Jin, Hui
Lv, Xueman
Chen, Jiajun
Anti-Hu Antibody-Associated Adie's Pupil and Paraneoplastic Sensorimotor Polyneuropathy Caused by Primary Mediastinal Small Cell Carcinoma
title Anti-Hu Antibody-Associated Adie's Pupil and Paraneoplastic Sensorimotor Polyneuropathy Caused by Primary Mediastinal Small Cell Carcinoma
title_full Anti-Hu Antibody-Associated Adie's Pupil and Paraneoplastic Sensorimotor Polyneuropathy Caused by Primary Mediastinal Small Cell Carcinoma
title_fullStr Anti-Hu Antibody-Associated Adie's Pupil and Paraneoplastic Sensorimotor Polyneuropathy Caused by Primary Mediastinal Small Cell Carcinoma
title_full_unstemmed Anti-Hu Antibody-Associated Adie's Pupil and Paraneoplastic Sensorimotor Polyneuropathy Caused by Primary Mediastinal Small Cell Carcinoma
title_short Anti-Hu Antibody-Associated Adie's Pupil and Paraneoplastic Sensorimotor Polyneuropathy Caused by Primary Mediastinal Small Cell Carcinoma
title_sort anti-hu antibody-associated adie's pupil and paraneoplastic sensorimotor polyneuropathy caused by primary mediastinal small cell carcinoma
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901962/
https://www.ncbi.nlm.nih.gov/pubmed/31849812
http://dx.doi.org/10.3389/fneur.2019.01236
work_keys_str_mv AT zhanglei antihuantibodyassociatedadiespupilandparaneoplasticsensorimotorpolyneuropathycausedbyprimarymediastinalsmallcellcarcinoma
AT luosi antihuantibodyassociatedadiespupilandparaneoplasticsensorimotorpolyneuropathycausedbyprimarymediastinalsmallcellcarcinoma
AT jinhui antihuantibodyassociatedadiespupilandparaneoplasticsensorimotorpolyneuropathycausedbyprimarymediastinalsmallcellcarcinoma
AT lvxueman antihuantibodyassociatedadiespupilandparaneoplasticsensorimotorpolyneuropathycausedbyprimarymediastinalsmallcellcarcinoma
AT chenjiajun antihuantibodyassociatedadiespupilandparaneoplasticsensorimotorpolyneuropathycausedbyprimarymediastinalsmallcellcarcinoma

Ejemplares similares