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Effect of Interleukin-15 Receptor Alpha Ablation on the Metabolic Responses to Moderate Exercise Simulated by in vivo Isometric Muscle Contractions
Lack of interleukin 15 receptor alpha (IL15RA) increases spontaneous activity, exercise capacity and protects from diet-induced obesity by enhancing muscle energy metabolism, suggesting a role as exercise mimetic for IL15RA antagonists. Using controlled in vivo muscle stimulation mimicking moderate...
Autores principales: | Loro, Emanuele, Jang, Cholsoon, Quinn, William J., Baur, Joseph A., Arany, Zoltan P., Khurana, Tejvir S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901992/ https://www.ncbi.nlm.nih.gov/pubmed/31849697 http://dx.doi.org/10.3389/fphys.2019.01439 |
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