Cell Intrinsic Deregulated ß-Catenin Signaling Promotes Expansion of Bone Marrow Derived Connective Tissue Type Mast Cells, Systemic Inflammation, and Colon Cancer

Mast cells constitutively express ß-catenin and expand in solid tumors such as colon and skin cancer. However, the role of ß-catenin signaling in mast cells and the cause or effect of mast cell expansion and tumor growth has yet to be established. In earlier studies we used mast cell depletion and p...

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Detalles Bibliográficos
Autores principales: Saadalla, Abdulrahman, Lima, Mariana Machado, Tsai, Funien, Osman, Abu, Singh, Mahendra Pal, Linden, David R., Dennis, Kristen L., Haeryfar, S. M. Mansour, Gurish, Michael F., Gounari, Fotini, Khazaie, Khashayarsha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902090/
https://www.ncbi.nlm.nih.gov/pubmed/31849960
http://dx.doi.org/10.3389/fimmu.2019.02777

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