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Mouse Models of Human Gastric Cancer Subtypes With Stomach-Specific CreERT2-Mediated Pathway Alterations

BACKGROUND & AIMS: Patterns of genetic alterations characterize different molecular subtypes of human gastric cancer. We aimed to establish mouse models of these subtypes. METHODS: We searched databases to identify genes with unique expression in the stomach epithelium, resulting in the identifi...

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Detalles Bibliográficos
Autores principales: Seidlitz, Therese, Chen, Yi-Ting, Uhlemann, Heike, Schölch, Sebastian, Kochall, Susan, Merker, Sebastian R., Klimova, Anna, Hennig, Alexander, Schweitzer, Christine, Pape, Kristin, Baretton, Gustavo B., Welsch, Thilo, Aust, Daniela E., Weitz, Jürgen, Koo, Bon-Kyoung, Stange, Daniel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: W.B. Saunders 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902245/
https://www.ncbi.nlm.nih.gov/pubmed/31585123
http://dx.doi.org/10.1053/j.gastro.2019.09.026