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The Structural Biology of Galectin-Ligand Recognition: Current Advances in Modeling Tools, Protein Engineering, and Inhibitor Design
Galectins (formerly known as “S-type lectins”) are a subfamily of soluble proteins that typically bind β-galactoside carbohydrates with high specificity. They are present in many forms of life, from nematodes and fungi to animals, where they perform a wide range of functions. Particularly in humans,...
Autores principales: | Modenutti, Carlos P., Capurro, Juan I. Blanco, Di Lella, Santiago, Martí, Marcelo A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902271/ https://www.ncbi.nlm.nih.gov/pubmed/31850312 http://dx.doi.org/10.3389/fchem.2019.00823 |
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