Splenomegaly impacts prognosis in essential thrombocythemia and polycythemia vera: A single center study

Splenomegaly is one of the major clinical manifestations of primary myelofibrosis and is common also in other chronic Philadelphia-negative myeloproliferative neoplasms, causing symptoms and signs and affecting quality of life of patients diagnosed with these diseases. We aimed to study the impact t...

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Autores principales: Accurso, Vincenzo, Santoro, Marco, Raso, Simona, Contrino, Angelo Davide, Casimiro, Paolo, Piazza, Florinda Di, Perez, Alessandro, Russo, Antonio, Siragusa, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902304/
https://www.ncbi.nlm.nih.gov/pubmed/31871612
http://dx.doi.org/10.4081/hr.2019.8281
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author Accurso, Vincenzo
Santoro, Marco
Raso, Simona
Contrino, Angelo Davide
Casimiro, Paolo
Piazza, Florinda Di
Perez, Alessandro
Russo, Antonio
Siragusa, Sergio
author_facet Accurso, Vincenzo
Santoro, Marco
Raso, Simona
Contrino, Angelo Davide
Casimiro, Paolo
Piazza, Florinda Di
Perez, Alessandro
Russo, Antonio
Siragusa, Sergio
author_sort Accurso, Vincenzo
collection PubMed
description Splenomegaly is one of the major clinical manifestations of primary myelofibrosis and is common also in other chronic Philadelphia-negative myeloproliferative neoplasms, causing symptoms and signs and affecting quality of life of patients diagnosed with these diseases. We aimed to study the impact that such alteration has on thrombotic risk and on the survival of patients with essential thrombocythemia and patients with Polycythemia Vera (PV). We studied the relationship between splenomegaly (and its grade), thrombosis and survival in 238 patients with et and 165 patients with PV followed at our center between January 1997 and May 2019.
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spelling pubmed-69023042019-12-23 Splenomegaly impacts prognosis in essential thrombocythemia and polycythemia vera: A single center study Accurso, Vincenzo Santoro, Marco Raso, Simona Contrino, Angelo Davide Casimiro, Paolo Piazza, Florinda Di Perez, Alessandro Russo, Antonio Siragusa, Sergio Hematol Rep Article Splenomegaly is one of the major clinical manifestations of primary myelofibrosis and is common also in other chronic Philadelphia-negative myeloproliferative neoplasms, causing symptoms and signs and affecting quality of life of patients diagnosed with these diseases. We aimed to study the impact that such alteration has on thrombotic risk and on the survival of patients with essential thrombocythemia and patients with Polycythemia Vera (PV). We studied the relationship between splenomegaly (and its grade), thrombosis and survival in 238 patients with et and 165 patients with PV followed at our center between January 1997 and May 2019. PAGEPress Publications, Pavia, Italy 2019-12-04 /pmc/articles/PMC6902304/ /pubmed/31871612 http://dx.doi.org/10.4081/hr.2019.8281 Text en ©Copyright: the Author(s), 2019 http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (by-nc 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Article
Accurso, Vincenzo
Santoro, Marco
Raso, Simona
Contrino, Angelo Davide
Casimiro, Paolo
Piazza, Florinda Di
Perez, Alessandro
Russo, Antonio
Siragusa, Sergio
Splenomegaly impacts prognosis in essential thrombocythemia and polycythemia vera: A single center study
title Splenomegaly impacts prognosis in essential thrombocythemia and polycythemia vera: A single center study
title_full Splenomegaly impacts prognosis in essential thrombocythemia and polycythemia vera: A single center study
title_fullStr Splenomegaly impacts prognosis in essential thrombocythemia and polycythemia vera: A single center study
title_full_unstemmed Splenomegaly impacts prognosis in essential thrombocythemia and polycythemia vera: A single center study
title_short Splenomegaly impacts prognosis in essential thrombocythemia and polycythemia vera: A single center study
title_sort splenomegaly impacts prognosis in essential thrombocythemia and polycythemia vera: a single center study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902304/
https://www.ncbi.nlm.nih.gov/pubmed/31871612
http://dx.doi.org/10.4081/hr.2019.8281
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