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Systemic RAGE ligands are upregulated in tuberculosis individuals with diabetes co-morbidity and modulated by anti-tuberculosis treatment and metformin therapy

BACKGROUND: Ligands of the receptor for advanced glycation end products (RAGE) are key signalling molecules in the innate immune system but their role in tuberculosis-diabetes comorbidity (TB-DM) has not been investigated. METHODS: We examined the systemic levels of soluble RAGE (sRAGE), advanced gl...

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Detalles Bibliográficos
Autores principales: Kumar, Nathella Pavan, Moideen, Kadar, Nancy, Arul, Viswanathan, Vijay, Shruthi, Basavaradhya S., Sivakumar, Shanmugam, Hissar, Syed, Kornfeld, Hardy, Babu, Subash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902343/
https://www.ncbi.nlm.nih.gov/pubmed/31818258
http://dx.doi.org/10.1186/s12879-019-4648-1