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Long non-coding XIST raises methylation of TIMP-3 promoter to regulate collagen degradation in osteoarthritic chondrocytes after tibial plateau fracture

BACKGROUND: Hypermethylation of gene promoters has been regarded as an epigenetic regulator for gene inactivation in the development of several diseases. In the current study, we aimed to explore how long noncoding RNA X-inactive specific transcript (lncRNA XIST) function in collagen degradation in...

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Detalles Bibliográficos
Autores principales:	Chen, Hongwei, Yang, Shengdi, Shao, Ruyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902347/ https://www.ncbi.nlm.nih.gov/pubmed/31815654 http://dx.doi.org/10.1186/s13075-019-2033-5

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