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Monoclonal immunoglobulin mediates complement activation in monoclonal gammopathy associated-C3 glomerulonephritis

BACKGROUND: C3 glomerulonephritis (C3GN) is a rare disease caused by inherited or acquired complement alternative pathway (CAP) dysregulation, which could also be secondary to monoclonal gammopathy of undetermined significance (MGUS). Herein, we described a patient presenting with C3GN and monoclona...

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Detalles Bibliográficos
Autores principales: Li, Lin-Lin, Li, Zhi-Ying, Wang, Su-Xia, Yu, Xiao-Juan, Tan, Ying, Wang, Yu, Yu, Feng, Zhao, Ming-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902416/
https://www.ncbi.nlm.nih.gov/pubmed/31823738
http://dx.doi.org/10.1186/s12882-019-1640-3