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Plasma sTNFR1 and IL8 for prognostic enrichment in sepsis trials: a prospective cohort study

BACKGROUND: Enrichment strategies improve therapeutic targeting and trial efficiency, but enrichment factors for sepsis trials are lacking. We determined whether concentrations of soluble tumor necrosis factor receptor-1 (sTNFR1), interleukin-8 (IL8), and angiopoietin-2 (Ang2) could identify sepsis...

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Detalles Bibliográficos
Autores principales:	Anderson, Brian J., Calfee, Carolyn S., Liu, Kathleen D., Reilly, John P., Kangelaris, Kirsten N., Shashaty, Michael G. S., Lazaar, Aili L., Bayliffe, Andrew I., Gallop, Robert J., Miano, Todd A., Dunn, Thomas G., Johansson, Erik, Abbott, Jason, Jauregui, Alejandra, Deiss, Thomas, Vessel, Kathryn, Belzer, Annika, Zhuo, Hanjing, Matthay, Michael A., Meyer, Nuala J., Christie, Jason D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902425/ https://www.ncbi.nlm.nih.gov/pubmed/31818332 http://dx.doi.org/10.1186/s13054-019-2684-2

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