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The Moraxella catarrhalis phase-variable DNA methyltransferase ModM3 is an epigenetic regulator that affects bacterial survival in an in vivo model of otitis media

BACKGROUND: Moraxella catarrhalis is a leading cause of otitis media (OM) and chronic obstructive pulmonary disease (COPD). M. catarrhalis contains a Type III DNA adenine methyltransferase (ModM) that is phase-variably expressed (i.e., its expression is subject to random, reversible ON/OFF switching...

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Detalles Bibliográficos
Autores principales: Blakeway, Luke V., Tan, Aimee, Jurcisek, Joseph A., Bakaletz, Lauren O., Atack, John M., Peak, Ian R., Seib, Kate L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902483/
https://www.ncbi.nlm.nih.gov/pubmed/31818247
http://dx.doi.org/10.1186/s12866-019-1660-y