An adaptive two-arm clinical trial using early endpoints to inform decision making: design for a study of sub-acromial spacers for repair of rotator cuff tendon tears

BACKGROUND: There is widespread concern across the clinical and research communities that clinical trials, powered for patient-reported outcomes, testing new surgical procedures are often expensive and time-consuming, particularly when the new intervention is shown to be no better than the standard....

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Detalles Bibliográficos
Autores principales: Parsons, Nick, Stallard, Nigel, Parsons, Helen, Wells, Philip, Underwood, Martin, Mason, James, Metcalfe, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902495/
https://www.ncbi.nlm.nih.gov/pubmed/31815651
http://dx.doi.org/10.1186/s13063-019-3708-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902495/
https://www.ncbi.nlm.nih.gov/pubmed/31815651
http://dx.doi.org/10.1186/s13063-019-3708-6

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