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Uev1A promotes breast cancer cell survival and chemoresistance through the AKT-FOXO1-BIM pathway

BACKGROUND: Ubiquitin-conjugating enzyme variant UEV1A is required for Ubc13-catalyzed K63-linked poly-ubiquitination that regulates several signaling pathways including NF-κB, MAPK and PI3K/AKT. Previous reports implicate UEV1A as a potential proto-oncogene and have shown that UEV1A promotes breast...

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Detalles Bibliográficos
Autores principales:	Wu, Zhaojia, Niu, Tong, Xiao, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902549/ https://www.ncbi.nlm.nih.gov/pubmed/31827405 http://dx.doi.org/10.1186/s12935-019-1050-4

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