Cargando…

Uev1A promotes breast cancer cell survival and chemoresistance through the AKT-FOXO1-BIM pathway

BACKGROUND: Ubiquitin-conjugating enzyme variant UEV1A is required for Ubc13-catalyzed K63-linked poly-ubiquitination that regulates several signaling pathways including NF-κB, MAPK and PI3K/AKT. Previous reports implicate UEV1A as a potential proto-oncogene and have shown that UEV1A promotes breast...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Zhaojia, Niu, Tong, Xiao, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902549/ https://www.ncbi.nlm.nih.gov/pubmed/31827405 http://dx.doi.org/10.1186/s12935-019-1050-4

Ejemplares similares

Uev1A promotes breast cancer cell migration by up-regulating CT45A expression via the AKT pathway
por: Niu, Tong, et al.
Publicado: (2021)

Uev1A-Ubc13 promotes colorectal cancer metastasis through regulating CXCL1 expression via NF-кB activation
por: Wu, Zhaojia, et al.
Publicado: (2018)

TUFT1 promotes metastasis and chemoresistance in triple negative breast cancer through the TUFT1/Rab5/Rac1 pathway
por: Liu, Weiguang, et al.
Publicado: (2019)

Ubiquitin-conjugating enzyme complex Uev1A-Ubc13 promotes breast cancer metastasis through nuclear factor-кB mediated matrix metalloproteinase-1 gene regulation
por: Wu, Zhaojia, et al.
Publicado: (2014)

Erratum to: Ubiquitin-conjugating enzyme complex Uev1A-Ubc13 promotes breast cancer metastasis through nuclear factor-кB mediated matrix metalloproteinase-1 gene regulation
por: Wu, Zhaojia, et al.
Publicado: (2017)

Idelalisib promotes Bim-dependent apoptosis through AKT/FoxO3a in hepatocellular carcinoma
por: Yue, Dan, et al.
Publicado: (2018)

Inhibition of FOXO1 by small interfering RNA enhances proliferation and inhibits apoptosis of papillary thyroid carcinoma cells via Akt/FOXO1/Bim pathway
por: Song, Hong-ming, et al.
Publicado: (2015)

Sphingosine Kinase 1 Regulates the Akt/FOXO3a/Bim Pathway and Contributes to Apoptosis Resistance in Glioma Cells
por: Guan, Hongyu, et al.
Publicado: (2011)

miR-96 exerts carcinogenic effect by activating AKT/GSK-3β/β-catenin signaling pathway through targeting inhibition of FOXO1 in hepatocellular carcinoma
por: Yang, Nanmu, et al.
Publicado: (2019)

FAM49B promotes breast cancer proliferation, metastasis, and chemoresistance by stabilizing ELAVL1 protein and regulating downstream Rab10/TLR4 pathway
por: Li, Yanhui, et al.
Publicado: (2021)

Extracellular HMGB1 interacts with RAGE and promotes chemoresistance in acute leukemia cells
por: Lai, Weixin, et al.
Publicado: (2021)

Bim and VDAC1 are hierarchically essential for mitochondrial ATF2 mediated cell death
por: Liu, Zhaoyun, et al.
Publicado: (2015)

Hedgehog/Gli1 signaling pathway regulates MGMT expression and chemoresistance to temozolomide in human glioblastoma
por: Wang, Ke, et al.
Publicado: (2017)

Rigorous characterization of urinary extracellular vesicles (uEVs) in the low centrifugation pellet - a neglected source for uEVs
por: Musante, Luca, et al.
Publicado: (2020)

MicroRNA-302a is involved in folate deficiency-induced apoptosis through the AKT-FOXO1-BIM pathway in mouse embryonic stem cells
por: Liang, Yan, et al.
Publicado: (2020)

Uev1A facilitates osteosarcoma differentiation by promoting Smurf1-mediated Smad1 ubiquitination and degradation
por: Zhang, Weiwei, et al.
Publicado: (2017)

Periostin promotes the proliferation and metastasis of osteosarcoma by increasing cell survival and activates the PI3K/Akt pathway
por: Xu, Chaojian, et al.
Publicado: (2022)

Hexokinases 2 promoted cell motility and distant metastasis by elevating fibronectin through Akt1/p-Akt1 in cervical cancer cells
por: Chen, Qian, et al.
Publicado: (2021)

Effects and Mechanism of Oxymatrine Combined with Compound Yinchen Granules on the Apoptosis of Hepatocytes through the Akt/FoxO3a/Bim Pathway
por: Zhang, Xian, et al.
Publicado: (2022)

Down-regulation of LINC00472 promotes osteosarcoma tumorigenesis by reducing FOXO1 expressions via miR-300
por: Zhang, Jingwei, et al.
Publicado: (2020)

JOSD1 promotes proliferation and chemoresistance of head and neck squamous cell carcinoma under the epigenetic regulation of BRD4
por: Jing, Chao, et al.
Publicado: (2021)

Chemotherapy resistance and metastasis-promoting effects of thyroid hormone in hepatocarcinoma cells are mediated by suppression of FoxO1 and Bim pathway
por: Chi, Hsiang-Cheng, et al.
Publicado: (2016)

IGHG1 upregulation promoted gastric cancer malignancy via AKT/GSK-3β/β-Catenin pathway
por: Li, Xinyu, et al.
Publicado: (2021)

CHIP Regulates AKT/FoxO/Bim Signaling in MCF7 and MCF10A Cells
por: Lv, Yanrong, et al.
Publicado: (2013)

Caveolin-1 induces lamellipodia formation via an Akt-dependent pathway
por: Chanvorachote, Pithi, et al.
Publicado: (2014)

LncRNA SNHG6 promotes chemoresistance through ULK1-induced autophagy by sponging miR-26a-5p in colorectal cancer cells
por: Wang, Xinke, et al.
Publicado: (2019)

The synthetic peptide CIGB-300 modulates CK2-dependent signaling pathways affecting the survival and chemoresistance of non-small cell lung cancer cell lines
por: Cirigliano, Stéfano M., et al.
Publicado: (2017)

Traxoprodil Produces Antidepressant-Like Behaviors in Chronic Unpredictable Mild Stress Mice through BDNF/ERK/CREB and AKT/FOXO/Bim Signaling Pathway
por: Wang, Yahui, et al.
Publicado: (2023)

A novel 4-gene signature for overall survival prediction in lung adenocarcinoma patients with lymph node metastasis
por: Wang, Yanfang, et al.
Publicado: (2019)

SKA3 promotes cell proliferation and migration in cervical cancer by activating the PI3K/Akt signaling pathway
por: Hu, Rong, et al.
Publicado: (2018)

Regorafenib induces Bim-mediated intrinsic apoptosis by blocking AKT-mediated FOXO3a nuclear export
por: Sun, Beini, et al.
Publicado: (2023)

EZR promotes pancreatic cancer proliferation and metastasis by activating FAK/AKT signaling pathway
por: Xu, Jian, et al.
Publicado: (2021)

Wilms’ tumour suppressor gene 1 (WT1) is involved in the carcinogenesis of Lung cancer through interaction with PI3K/Akt pathway
por: Wang, Xi, et al.
Publicado: (2013)

Macrophage polarization-associated lnc-Ma301 interacts with caprin-1 to inhibit hepatocellular carcinoma metastasis through the Akt/Erk1 pathway
por: Luo, Hong-Lin, et al.
Publicado: (2021)

YY1 activates EMI2 and promotes the progression of cholangiocarcinoma through the PI3K/Akt signaling axis
por: Zhou, Shuai, et al.
Publicado: (2021)

Ubiquitin-specific protease 7 is a drug-able target that promotes hepatocellular carcinoma and chemoresistance
por: Zhang, Wei, et al.
Publicado: (2020)

The stem cell factor antibody enhances the chemotherapeutic effect of adriamycin on chemoresistant breast cancer cells
por: Jelly, Neil D, et al.
Publicado: (2012)

TRIM27 promotes the development of esophagus cancer via regulating PTEN/AKT signaling pathway
por: Ma, Liang, et al.
Publicado: (2019)

FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons
por: Gilley, Jonathan, et al.
Publicado: (2003)

SH2B1 promotes NSCLC cell proliferation through PI3K/Akt/mTOR signaling cascade
por: Wang, Shaoqiang, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_lg6ooat7cacrchemgejt40l86a