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An unusual case of steroid responsive idiopathic ectopic calcification

This case explores an unusual calcified lesion of the hand and its dramatic response to steroids. A 30-year-old lady presented to rheumatology with a 1-year history of swelling on the radial side of her right middle metacarpophalangeal joint. Over a 2-week period, she had developed swelling througho...

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Detalles Bibliográficos
Autores principales: Tsoi, Kevin, Hughes, Rod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902625/
https://www.ncbi.nlm.nih.gov/pubmed/31844527
http://dx.doi.org/10.1093/omcr/omz108
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author Tsoi, Kevin
Hughes, Rod
author_facet Tsoi, Kevin
Hughes, Rod
author_sort Tsoi, Kevin
collection PubMed
description This case explores an unusual calcified lesion of the hand and its dramatic response to steroids. A 30-year-old lady presented to rheumatology with a 1-year history of swelling on the radial side of her right middle metacarpophalangeal joint. Over a 2-week period, she had developed swelling throughout her right hand. She was treated with intramuscular methylprednisolone injection and a weaning course of prednisolone. A series of photos and X-rays demonstrates the resolution of swelling and calcification after steroid treatment. This case reports a chronic calcified mass associated with an acute inflammatory episode in the hand. This is likely to represent rupture of a calcific deposit with the release of crystals into the soft tissue. While there is prior literature on treatment with bisphosphonates or surgery, a fast and complete response to modest dose steroids suggests that this would be the first treatment to try in such a case.
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spelling pubmed-69026252019-12-16 An unusual case of steroid responsive idiopathic ectopic calcification Tsoi, Kevin Hughes, Rod Oxf Med Case Reports Case Report This case explores an unusual calcified lesion of the hand and its dramatic response to steroids. A 30-year-old lady presented to rheumatology with a 1-year history of swelling on the radial side of her right middle metacarpophalangeal joint. Over a 2-week period, she had developed swelling throughout her right hand. She was treated with intramuscular methylprednisolone injection and a weaning course of prednisolone. A series of photos and X-rays demonstrates the resolution of swelling and calcification after steroid treatment. This case reports a chronic calcified mass associated with an acute inflammatory episode in the hand. This is likely to represent rupture of a calcific deposit with the release of crystals into the soft tissue. While there is prior literature on treatment with bisphosphonates or surgery, a fast and complete response to modest dose steroids suggests that this would be the first treatment to try in such a case. Oxford University Press 2019-12-09 /pmc/articles/PMC6902625/ /pubmed/31844527 http://dx.doi.org/10.1093/omcr/omz108 Text en © The Author(s) 2019. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Tsoi, Kevin
Hughes, Rod
An unusual case of steroid responsive idiopathic ectopic calcification
title An unusual case of steroid responsive idiopathic ectopic calcification
title_full An unusual case of steroid responsive idiopathic ectopic calcification
title_fullStr An unusual case of steroid responsive idiopathic ectopic calcification
title_full_unstemmed An unusual case of steroid responsive idiopathic ectopic calcification
title_short An unusual case of steroid responsive idiopathic ectopic calcification
title_sort unusual case of steroid responsive idiopathic ectopic calcification
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902625/
https://www.ncbi.nlm.nih.gov/pubmed/31844527
http://dx.doi.org/10.1093/omcr/omz108
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