Cargando…
The annexin A1/FPR2 signaling axis expands alveolar macrophages, limits viral replication, and attenuates pathogenesis in the murine influenza A virus infection model
Pattern recognition receptors (PRRs) are key elements in the innate immune response. Formyl peptide receptor (FPR) 2 is a PRR that, in addition to proinflammatory, pathogen-derived compounds, also recognizes the anti-inflammatory endogenous ligand annexin A1 (AnxA1). Because the contribution of this...
Autores principales: | Schloer, Sebastian, Hübel, Nicole, Masemann, Dörthe, Pajonczyk, Denise, Brunotte, Linda, Ehrhardt, Christina, Brandenburg, Lars-Ove, Ludwig, Stephan, Gerke, Volker, Rescher, Ursula |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Federation of American Societies for Experimental Biology
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902725/ https://www.ncbi.nlm.nih.gov/pubmed/31398292 http://dx.doi.org/10.1096/fj.201901265R |
Ejemplares similares
-
Annexins in Translational Research: Hidden Treasures to Be Found
por: Schloer, Sebastian, et al.
Publicado: (2018) -
Annexin A6-Balanced Late Endosomal Cholesterol Controls Influenza A Replication and Propagation
por: Musiol, Agnes, et al.
Publicado: (2013) -
Targeting the endolysosomal host-SARS-CoV-2 interface by clinically licensed functional inhibitors of acid sphingomyelinase (FIASMA) including the antidepressant fluoxetine
por: Schloer, Sebastian, et al.
Publicado: (2020) -
Exploring Biased Agonism at FPR1 as a Means to Encode Danger Sensing †
por: Gröper, Jieny, et al.
Publicado: (2020) -
Special Issue “Recent Developments in Annexin Biology”
por: Rescher, Ursula, et al.
Publicado: (2020)