ULK2 is essential for degradation of ubiquitinated protein aggregates and homeostasis in skeletal muscle

Basal protein turnover, which largely relies on the degradation of ubiquitinated substrates, is instrumental for maintenance of muscle mass and function. However, the regulation of ubiquitinated protein degradation in healthy, nonatrophying skeletal muscle is still evolving, and potential tissue-spe...

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Detalles Bibliográficos
Autores principales: Fuqua, Jordan D., Mere, Caleb P., Kronemberger, Ana, Blomme, Jay, Bae, Dam, Turner, Kristen D., Harris, Matthew P., Scudese, Estevão, Edwards, Mitchell, Ebert, Scott M., de Sousa, Luís G. O., Bodine, Sue C., Yang, Ling, Adams, Christopher M., Lira, Vitor A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902739/
https://www.ncbi.nlm.nih.gov/pubmed/31361156
http://dx.doi.org/10.1096/fj.201900766R

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