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A green, economical synthesis of β-ketonitriles and trifunctionalized building blocks from esters and lactones
The acylation of the acetonitrile anion with lactones and esters in ethereal solvents was successfully exploited using inexpensive KOt-Bu to obtain a variety of β-ketonitriles and trifunctionalized building blocks, including useful O-unprotected diols. It was discovered that lactones react to produc...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902896/ https://www.ncbi.nlm.nih.gov/pubmed/31839839 http://dx.doi.org/10.3762/bjoc.15.287 |