An (1)H NMR study of the cytarabine degradation in clinical conditions to avoid drug waste, decrease therapy costs and improve patient compliance in acute leukemia

Cytarabine, the 4-amino-1-(β-D-arabinofuranosyl)-2(1H)-pyrimidinone, (ARA-C) is an antimetabolite cytidine analogue used worldwide as key drug in the management of leukaemia. As specified in the manufacturers’ instructions, once the components—sterile water and cytarabine powder—are unpackaged and m...

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Detalles Bibliográficos
Autores principales: Cerchione, Claudio, Martinelli, Giovanni, Pedatella, Silvana, De Nisco, Mauro, Pugliese, Novella, Manfra, Michele, Marra, Nicoletta, Ronconi, Sonia, De Giorgi, Ugo, Altini, Mattia, Simonetti, Giorgia, Di Rorà, Andrea Ghelli Luserna, Bravaccini, Sara, Catalano, Lucio, Dora Iula, Vita, Pagano, Francesco, Picardi, Marco, Bolognese, Adele, Pane, Fabrizio, Martinelli, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Clinical Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6903421/
https://www.ncbi.nlm.nih.gov/pubmed/31633499
http://dx.doi.org/10.1097/CAD.0000000000000850

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