Developmental expression of human tau in Drosophila melanogaster glial cells induces motor deficits and disrupts maintenance of PNS axonal integrity, without affecting synapse formation

Tauopathies are a class of neurodegenerative diseases characterized by the abnormal phosphorylation and accumulation of the microtubule-associated protein, tau, in both neuronal and glial cells. Though tau pathology in glial cells is a prominent feature of many of these disorders, the pathological c...

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Detalles Bibliográficos
Autores principales: Scarpelli, Enrico M., Trinh, Van Y., Tashnim, Zarrin, Krans, Jacob L., Keller, Lani C., Colodner, Kenneth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6903755/
https://www.ncbi.nlm.nih.gov/pubmed/31821364
http://dx.doi.org/10.1371/journal.pone.0226380

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