Cargando…

Genome-Wide Association Study of Microscopic Colitis in the UK Biobank Confirms Immune-Related Pathogenesis

BACKGROUND AND AIMS: The causes of microscopic colitis are currently poorly understood. Previous reports have found clinical associations with coeliac disease and genetic associations at the human leukocyte antigen [HLA] locus on the ancestral 8.1 haplotype. We investigated pharmacological and genet...

Descripción completa

Detalles Bibliográficos
Autores principales:	Green, Harry D, Beaumont, Robin N, Thomas, Amanda, Hamilton, Benjamin, Wood, Andrew R, Sharp, Seth, Jones, Samuel E, Tyrrell, Jessica, Walker, Gareth, Goodhand, James, Kennedy, Nicholas A, Ahmad, Tariq, Weedon, Michael N
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6903793/ https://www.ncbi.nlm.nih.gov/pubmed/31125052 http://dx.doi.org/10.1093/ecco-jcc/jjz104

Ejemplares similares

Prevalence of Fabry disease-causing variants in the UK Biobank
por: Gilchrist, Mark, et al.
Publicado: (2023)

Gene–obesogenic environment interactions in the UK Biobank study
por: Tyrrell, Jessica, et al.
Publicado: (2017)

Genetic evidence that higher central adiposity causes gastro-oesophageal reflux disease: a Mendelian randomization study
por: Green, Harry D, et al.
Publicado: (2020)

Height, body mass index, and socioeconomic status: mendelian randomisation study in UK Biobank
por: Tyrrell, Jessica, et al.
Publicado: (2016)

Microscopic Colitis: Pathogenesis and Diagnosis
por: Songtanin, Busara, et al.
Publicado: (2023)

IgA Nephropathy Genetic Risk Score to Estimate the Prevalence of IgA Nephropathy in UK Biobank
por: Sukcharoen, Kittiya, et al.
Publicado: (2020)

Genetic predictors of participation in optional components of UK Biobank
por: Tyrrell, Jessica, et al.
Publicado: (2021)

Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants
por: Pilling, Luke C., et al.
Publicado: (2016)

Prevalence, Pathogenesis, Diagnosis, and Management of Microscopic Colitis
por: Gentile, Nicole, et al.
Publicado: (2018)

Applying a genetic risk score for prostate cancer to men with lower urinary tract symptoms in primary care to predict prostate cancer diagnosis: a cohort study in the UK Biobank
por: Green, Harry D., et al.
Publicado: (2022)

Events in Early Life are Associated with Female Reproductive Ageing: A UK Biobank Study
por: Ruth, Katherine S., et al.
Publicado: (2016)

NF-kB pathway is involved in microscopic colitis pathogenesis
por: Pisani, Laura Francesca, et al.
Publicado: (2022)

Effects of body mass index on relationship status, social contact and socio-economic position: Mendelian randomization and within-sibling study in UK Biobank
por: Howe, Laura D, et al.
Publicado: (2019)

Membranous nephropathy in the UK Biobank
por: Hamilton, Patrick, et al.
Publicado: (2023)

Ulcerative colitis increases risk of hypertension in a UK biobank cohort study
por: He, Jinshen, et al.
Publicado: (2022)

Parental diabetes and birthweight in 236 030 individuals in the UK Biobank Study
por: Tyrrell, Jessica S, et al.
Publicado: (2013)

Physician-Confirmed and Administrative Definitions of Stroke in UK Biobank Reflect the Same Underlying Genetic Trait
por: Rannikmäe, Kristiina, et al.
Publicado: (2022)

Is Microscopic Colitis Really Microscopic?
por: Park, Young Sook, et al.
Publicado: (2015)

Is occupational physical activity associated with mortality in UK Biobank?
por: Pearce, Matthew, et al.
Publicado: (2021)

Identification and analysis of individuals who deviate from their genetically-predicted phenotype
por: Hawkes, Gareth, et al.
Publicado: (2023)

Identification and analysis of individuals who deviate from their genetically-predicted phenotype
por: Hawkes, Gareth, et al.
Publicado: (2023)

Associations with photoreceptor thickness measures in the UK Biobank
por: Chua, Sharon Y. L., et al.
Publicado: (2019)

Human Cytomegalovirus and Risk of Incident Cardiovascular Disease in UK Biobank
por: Yates, Tom A, et al.
Publicado: (2021)

A genome-wide association study identifies 5 loci associated with frozen shoulder and implicates diabetes as a causal risk factor
por: Green, Harry D., et al.
Publicado: (2021)

Controversials of Microscopic Colitis
por: Mihaly, Emese, et al.
Publicado: (2021)

Microscopic colitis: an update
por: Fărcaş, Radu A., et al.
Publicado: (2022)

Healthy living and cancer: evidence from UK Biobank
por: Elwood, Peter C, et al.
Publicado: (2018)

Development and Standardization of an Improved Type 1 Diabetes Genetic Risk Score for Use in Newborn Screening and Incident Diagnosis
por: Sharp, Seth A., et al.
Publicado: (2019)

Associations and limited shared genetic aetiology between bipolar disorder and cardiometabolic traits in the UK Biobank
por: Fürtjes, Anna E., et al.
Publicado: (2022)

The UK Biobank resource with deep phenotyping and genomic data
por: Bycroft, Clare, et al.
Publicado: (2018)

Frequency and phenotype of type 1 diabetes in the first six decades of life: a cross-sectional, genetically stratified survival analysis from UK Biobank
por: Thomas, Nicholas J, et al.
Publicado: (2018)

Genome-wide association studies of brain imaging phenotypes in UK Biobank
por: Elliott, Lloyd T., et al.
Publicado: (2018)

Clinical features of UK Biobank subjects carrying loss of function variants in genes implicated in schizophrenia pathogenesis
por: Curtis, D.
Publicado: (2022)

Intakes of major food groups in China and UK: results from 100,000 adults in the China Kadoorie biobank and UK biobank
por: Papier, Keren, et al.
Publicado: (2022)

Altered microbiota in microscopic colitis
por: Fischer, Hans, et al.
Publicado: (2015)

Microbial Associations With Microscopic Colitis
por: Sun, Shan, et al.
Publicado: (2022)

UK Biobank: a globally important resource for cancer research
por: Conroy, Megan C., et al.
Publicado: (2022)

Su1190 IS THERE AN ASSOCIATION BETWEEN SUBSTANCE DEPENDENCE AND MICROSCOPIC COLITIS OR EOSINOPHILIC COLITIS?
por: Alshati, Ali, et al.
Publicado: (2020)

Age and cognitive decline in the UK Biobank
por: Cornelis, Marilyn C., et al.
Publicado: (2019)

UK Biobank: opportunities for cardiovascular research
por: Littlejohns, Thomas J, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_qg9oooncjg1l2i4o3c01e9n6l3