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Spautin-1, a novel autophagy inhibitor, enhances imatinib-induced apoptosis in chronic myeloid leukemia

Imatinib mesylate (IM), a targeted competitive inhibitor of the BCR-ABL tyrosine kinase, has revolutionized the clinical treatment of chronic myeloid leukemia (CML). However, resistance and intolerance are still a challenge in the treatment of CML. Autophagy has been proposed to play a role in IM re...

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Detalles Bibliográficos
Autores principales:	Shao, Shan, Li, Su, Qin, Youwen, Wang, Xiaorui, Yang, Yining, Bai, Haitao, Zhou, Lili, Zhao, Chuxian, Wang, Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904104/ https://www.ncbi.nlm.nih.gov/pubmed/24585095 http://dx.doi.org/10.3892/ijo.2014.2313

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