Cargando…

The Botanical Glycoside Oleandrin Inhibits Human T-cell Leukemia Virus Type-1 Infectivity and Env-Dependent Virological Synapse Formation

At present, there are no antiretroviral drugs that inhibit incorporation of the envelope glycoprotein into newly-synthesized virus particles. The botanical glycoside, oleandrin, derived from extracts of Nerium oleander, has previously been shown to reduce the levels of the gp120 envelope glycoprotei...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hutchison, Tetiana, Yapindi, Laçin, Malu, Aditi, Newman, Robert A, Sastry, K Jagannadha, Harrod, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904119/ https://www.ncbi.nlm.nih.gov/pubmed/31824586 http://dx.doi.org/10.35248/1948-5964.19.11.184

Ejemplares similares

Antiviral Effects of Oleandrin
por: Newman, Robert A, et al.
Publicado: (2020)

Antiviral effects of oleandrin
por: Newman, R., et al.
Publicado: (2021)

Oleandrin: A cardiac glycosides with potent cytotoxicity
por: Kumar, Arvind, et al.
Publicado: (2013)

siRNA-Inhibition of TIGAR Hypersensitizes Human Papillomavirus-Transformed Cells to Apoptosis Induced by Chemotherapy Drugs that Cause Oxidative Stress
por: Yapindi, Lacin, et al.
Publicado: (2021)

Efficacy of oleandrin and PBI-05204 against bovine viruses of importance to commercial cattle health
por: Newman, Robert A., et al.
Publicado: (2022)

Retraction: Oleandrin: A Cardiac Glycosides with Potent Cytotoxicity
Publicado: (2016)

Differential Activities of the Botanical Extract PBI-05204 and Oleandrin on Innate Immune Functions under Viral Challenge Versus Inflammatory Culture Conditions
por: Jensen, Gitte S., et al.
Publicado: (2023)

Antiviral activity of oleandrin and a defined extract of Nerium oleander against SARS-CoV-2
por: Plante, Kenneth S., et al.
Publicado: (2021)

A Replication-Competent HIV Clone Carrying GFP-Env Reveals Rapid Env Recycling at the HIV-1 T Cell Virological Synapse
por: Wang, Lili, et al.
Publicado: (2021)

Sequential trafficking of Env and Gag to HIV-1 T cell virological synapses revealed by live imaging
por: Wang, Lili, et al.
Publicado: (2019)

The HTLV-1 latency-maintenance factor p30II activates p53-dependent metabolic effectors to promote oncogene-activation and aberrant lymphoproliferation
por: Harrod, Robert, et al.
Publicado: (2015)

The effect of 5α-oleandrin on keloid fibroblast activities
por: Dachlan, Ishandono, et al.
Publicado: (2019)

Oleandrin and Its Derivative Odoroside A, Both Cardiac Glycosides, Exhibit Anticancer Effects by Inhibiting Invasion via Suppressing the STAT-3 Signaling Pathway
por: Ko, Young Shin, et al.
Publicado: (2018)

Development and Validation of a UHPLC-ESI-MS/MS Method for Quantification of Oleandrin and Other Cardiac Glycosides and Evaluation of Their Levels in Herbs and Spices from the Belgian Market
por: Malysheva, Svetlana V., et al.
Publicado: (2020)

Oleandrin, a cardiac glycoside, induces immunogenic cell death via the PERK/elF2α/ATF4/CHOP pathway in breast cancer
por: Li, Xiaoxi, et al.
Publicado: (2021)

T Cell Polarization at the Virological Synapse
por: Jolly, Clare
Publicado: (2010)

The HTLV-1 Virological Synapse
por: Nejmeddine, Mohamed, et al.
Publicado: (2010)

Regulation of Intrinsic and Extrinsic Apoptotic Pathways in Osteosarcoma Cells Following Oleandrin Treatment
por: Ma, Yunlong, et al.
Publicado: (2016)

HIV-1 Virological Synapse is not Simply a Copycat of the Immunological Synapse
por: Vasiliver-Shamis, Gaia, et al.
Publicado: (2010)

Oleandrin induces DNA damage responses in cancer cells by suppressing the expression of Rad51
por: Bao, Zhengqiang, et al.
Publicado: (2016)

Cytotoxicity of Oleandrin Is Mediated by Calcium Influx and by Increased Manganese Uptake in Saccharomyces cerevisiae Cells
por: Ruta, Lavinia L., et al.
Publicado: (2020)

Virological Synapse for Cell-Cell Spread of Viruses
por: Garcia, Eduardo, et al.
Publicado: (2006)

HIV-1 Cell to Cell Transfer across an Env-induced, Actin-dependent Synapse
por: Jolly, Clare, et al.
Publicado: (2004)

HIV-1 Virological Synapse: Live Imaging of Transmission
por: Feldmann, Jerome, et al.
Publicado: (2010)

Investigating contact-induced T cell polarisation at virological synapses
por: Starling, Shimona, et al.
Publicado: (2013)

Oleandrin: A Systematic Review of its Natural Sources, Structural Properties, Detection Methods, Pharmacokinetics and Toxicology
por: Zhai, Jinxiao, et al.
Publicado: (2022)

Envés
por: Amara, Luigi, 1971-
Publicado: (2003)

104 Cell-to-cell transmission of HIV: role of virological synapse
por: Mazurov, DV, et al.
Publicado: (2014)

Phylogenetic and Structural Diversity in the Feline Leukemia Virus Env Gene
por: Watanabe, Shinya, et al.
Publicado: (2013)

Inhibition of oleandrin on the proliferation show and invasion of osteosarcoma cells in vitro by suppressing Wnt/β-catenin signaling pathway
por: Ma, Yunlong, et al.
Publicado: (2015)

Human T-Lymphotropic Virus-1 Visualized at the Virological Synapse by Electron Tomography
por: Majorovits, Endre, et al.
Publicado: (2008)

Unique Features of HIV-1 Spread through T Cell Virological Synapses
por: Alvarez, Raymond A., et al.
Publicado: (2014)

Genotypes diversity of env gene of Bovine leukemia virus in Western Siberia
por: Blazhko, Natalia, et al.
Publicado: (2020)

Oleandrin synergizes with cisplatin in human osteosarcoma cells by enhancing cell apoptosis through activation of the p38 MAPK signaling pathway
por: Yong, Lei, et al.
Publicado: (2018)

Contact-Induced Mitochondrial Polarization Supports HIV-1 Virological Synapse Formation
por: Groppelli, Elisabetta, et al.
Publicado: (2014)

LFA-1 Engagement Triggers T Cell Polarization at the HIV-1 Virological Synapse
por: Starling, Shimona, et al.
Publicado: (2016)

HIV Reactivation in Latently Infected Cells with Virological Synapse-Like Cell Contact
por: Okutomi, Toshiki, et al.
Publicado: (2020)

Imaging of HIV-1 Envelope-induced Virological Synapse and Signaling on Synthetic Lipid Bilayers
por: Prins, Kathleen C., et al.
Publicado: (2012)

XENOGENIZATION OF TUMOR CELLS BY TRANSFECTION WITH PLASMID CONTAINING env GENE OF FRIEND LEUKEMIA VIRUS
por: Sugiura, Chihiro, et al.
Publicado: (1988)

The regulated secretory pathway in CD4(+)T cells contributes to HIV-1 transmission at the virological synapse
por: Jolly, Clare, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_i7lpr478dienf81i39q0uthr5v