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Entry by multiple picornaviruses is dependent on a pathway that includes TNK2, WASL, and NCK1

Comprehensive knowledge of the host factors required for picornavirus infection would facilitate antiviral development. Here we demonstrate roles for three human genes, TNK2, WASL, and NCK1, in infection by multiple picornaviruses. CRISPR deletion of TNK2, WASL, or NCK1 reduced encephalomyocarditis...

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Detalles Bibliográficos
Autores principales:	Jiang, Hongbing, Leung, Christian, Tahan, Stephen, Wang, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Microbiology and Infectious Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904212/ https://www.ncbi.nlm.nih.gov/pubmed/31769754 http://dx.doi.org/10.7554/eLife.50276

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