Multiple kinesins induce tension for smooth cargo transport

How cargoes move within a crowded cell—over long distances and at speeds nearly the same as when moving on unimpeded pathway—has long been mysterious. Through an in vitro force-gliding assay, which involves measuring nanometer displacement and piconewtons of force, we show that multiple mammalian ki...

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Detalles Bibliográficos
Autores principales: Tjioe, Marco, Shukla, Saurabh, Vaidya, Rohit, Troitskaia, Alice, Bookwalter, Carol S, Trybus, Kathleen M, Chemla, Yann R, Selvin, Paul R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904222/
https://www.ncbi.nlm.nih.gov/pubmed/31670658
http://dx.doi.org/10.7554/eLife.50974

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904222/
https://www.ncbi.nlm.nih.gov/pubmed/31670658
http://dx.doi.org/10.7554/eLife.50974

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