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Characterization of Human Dosage-Sensitive Transcription Factor Genes
Copy number changes in protein-coding genes are detrimental if the consequent changes in protein concentrations disrupt essential cellular functions. The dosage sensitivity of transcription factor (TF) genes is particularly interesting because their products are essential in regulating the expressio...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904359/ https://www.ncbi.nlm.nih.gov/pubmed/31867040 http://dx.doi.org/10.3389/fgene.2019.01208 |