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Characterization of Human Dosage-Sensitive Transcription Factor Genes

Copy number changes in protein-coding genes are detrimental if the consequent changes in protein concentrations disrupt essential cellular functions. The dosage sensitivity of transcription factor (TF) genes is particularly interesting because their products are essential in regulating the expressio...

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Detalles Bibliográficos
Autores principales:	Ni, Zhihua, Zhou, Xiao-Yu, Aslam, Sidra, Niu, Deng-Ke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904359/ https://www.ncbi.nlm.nih.gov/pubmed/31867040 http://dx.doi.org/10.3389/fgene.2019.01208

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