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Impact of Polypharmacy and P-Glycoprotein- and CYP3A4-Modulating Drugs on Safety and Efficacy of Oral Anticoagulation Therapy in Patients with Atrial Fibrillation

PURPOSE: To study whether polypharmacy or drug–drug interactions have differential effect on safety and efficacy in patients treated with direct oral anticoagulants (DOACs) versus warfarin. METHODS: We performed a systematic review and meta-analysis of studies that randomized patients with atrial fi...

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Detalles Bibliográficos
Autores principales:	Harskamp, Ralf E., Teichert, Martina, Lucassen, Wim A. M., van Weert, Henk C. P. M., Lopes, Renato D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2019
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904377/ https://www.ncbi.nlm.nih.gov/pubmed/31520256 http://dx.doi.org/10.1007/s10557-019-06907-8

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