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Monkeys mutant for PKD1 recapitulate human autosomal dominant polycystic kidney disease

Autosomal dominant polycystic kidney disease (ADPKD) caused by PKD1 mutations is one of the most common hereditary disorders. However, the key pathological processes underlying cyst development and exacerbation in pre-symptomatic stages remain unknown, because rodent models do not recapitulate criti...

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Detalles Bibliográficos
Autores principales:	Tsukiyama, Tomoyuki, Kobayashi, Kenichi, Nakaya, Masataka, Iwatani, Chizuru, Seita, Yasunari, Tsuchiya, Hideaki, Matsushita, Jun, Kitajima, Kahoru, Kawamoto, Ikuo, Nakagawa, Takahiro, Fukuda, Koji, Iwakiri, Teppei, Izumi, Hiroyuki, Itagaki, Iori, Kume, Shinji, Maegawa, Hiroshi, Nishinakamura, Ryuichi, Nishio, Saori, Nakamura, Shinichiro, Kawauchi, Akihiro, Ema, Masatsugu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904451/ https://www.ncbi.nlm.nih.gov/pubmed/31822676 http://dx.doi.org/10.1038/s41467-019-13398-6

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