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Transcriptional correlates of the pathological phenotype in a Huntington’s disease mouse model

Huntington disease (HD) is a fatal neurodegenerative disorder without a cure that is caused by an aberrant expansion of CAG repeats in exon 1 of the huntingtin (HTT) gene. Although a negative correlation between the number of CAG repeats and the age of disease onset is established, additional factor...

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Detalles Bibliográficos
Autores principales:	Gallardo-Orihuela, Andrea, Hervás-Corpión, Irati, Hierro-Bujalance, Carmen, Sanchez-Sotano, Daniel, Jiménez-Gómez, Gema, Mora-López, Francisco, Campos-Caro, Antonio, Garcia-Alloza, Monica, Valor, Luis M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904489/ https://www.ncbi.nlm.nih.gov/pubmed/31822756 http://dx.doi.org/10.1038/s41598-019-55177-9

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