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Evaluation of binding and inhibition mechanism of dietary phytochemicals with sphingosine kinase 1: Towards targeted anticancer therapy

Sphingosine kinase 1 (SphK1) has recently gained attention as a potential drug target for its association with cancer and other inflammatory diseases. Here, we have investigated the binding affinity of dietary phytochemicals viz., ursolic acid, capsaicin, DL-α tocopherol acetate, quercetin, vanillin...

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Detalles Bibliográficos
Autores principales:	Gupta, Preeti, Mohammad, Taj, Dahiya, Rashmi, Roy, Sonam, Noman, Omar Mohammed Ali, Alajmi, Mohamed F., Hussain, Afzal, Hassan, Md. Imtaiyaz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904568/ https://www.ncbi.nlm.nih.gov/pubmed/31822735 http://dx.doi.org/10.1038/s41598-019-55199-3

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