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Pharmacological myeloperoxidase (MPO) inhibition in an obese/hypertensive mouse model attenuates obesity and liver damage, but not cardiac remodeling
Lifestyle factors are important drivers of chronic diseases, including cardiovascular syndromes, with low grade inflammation as a central player. Attenuating myeloperoxidase (MPO) activity, an inflammatory enzyme associated with obesity, hypertension and heart failure, could have protective effects...
Autores principales: | Piek, Arnold, Koonen, Debby P. Y., Schouten, Elisabeth-Maria, Lindtstedt, Eva L., Michaëlsson, Erik, de Boer, Rudolf A., Silljé, Herman H. W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904581/ https://www.ncbi.nlm.nih.gov/pubmed/31822739 http://dx.doi.org/10.1038/s41598-019-55263-y |
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