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Glycolytic suppression dramatically changes the intracellular metabolic profile of multiple cancer cell lines in a mitochondrial metabolism-dependent manner

Most cancer cells rely on glycolysis to generate ATP, even when oxygen is available. However, merely inhibiting the glycolysis is insufficient for the eradication of cancer cells. One main reason for this is that cancer cells have the potential to adapt their metabolism to their environmental condit...

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Detalles Bibliográficos
Autores principales: Shiratori, Reika, Furuichi, Kenta, Yamaguchi, Masashi, Miyazaki, Natsumi, Aoki, Haruna, Chibana, Hiroji, Ito, Kousei, Aoki, Shigeki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904735/
https://www.ncbi.nlm.nih.gov/pubmed/31822748
http://dx.doi.org/10.1038/s41598-019-55296-3