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Glycolytic suppression dramatically changes the intracellular metabolic profile of multiple cancer cell lines in a mitochondrial metabolism-dependent manner
Most cancer cells rely on glycolysis to generate ATP, even when oxygen is available. However, merely inhibiting the glycolysis is insufficient for the eradication of cancer cells. One main reason for this is that cancer cells have the potential to adapt their metabolism to their environmental condit...
Autores principales: | Shiratori, Reika, Furuichi, Kenta, Yamaguchi, Masashi, Miyazaki, Natsumi, Aoki, Haruna, Chibana, Hiroji, Ito, Kousei, Aoki, Shigeki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904735/ https://www.ncbi.nlm.nih.gov/pubmed/31822748 http://dx.doi.org/10.1038/s41598-019-55296-3 |
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